Cockcroft-Gault Creatinine Clearance Calculator
This estimates creatinine clearance, a measure of kidney function that many drug labels still use for dose adjustment. It is not normalised to body surface area, so it can differ from eGFR.
| Result | Interpretation |
|---|---|
| 90 and above | Normal (>=90) |
| 60 to 90 | Mild decrease (60-89) |
| 30 to 60 | Moderate decrease (30-59) |
| 15 to 30 | Severe decrease (15-29) |
| Below 15 | Kidney failure (<15) |
Source: Cockcroft DW, Gault MH. Prediction of creatinine clearance from serum creatinine. Nephron 1976;16(1):31-41. (doi:10.1159/000180580)
This calculator runs entirely in your browser. Enable JavaScript to use the interactive version. Nothing you enter is sent to a server.
For kidney-function staging, see the eGFR calculator (CKD-EPI 2021), which is normalized to body surface area.
FAQs
What is creatinine clearance and how does it differ from eGFR?
Creatinine clearance estimates how much blood your kidneys clear of creatinine each minute. Unlike eGFR, it is not adjusted for body surface area, which is why the two numbers can differ. Many drug labels were written using Cockcroft-Gault, so it is still widely used for dosing.
When should I use Cockcroft-Gault instead of eGFR?
Cockcroft-Gault is most useful for adjusting doses of medications that are cleared by the kidneys, because much of the dosing evidence was built on it. For staging chronic kidney disease, eGFR with the CKD-EPI 2021 equation is preferred.
Which weight should I enter?
This calculator uses the weight you enter directly. In clinical practice, clinicians sometimes use ideal or adjusted body weight in certain situations, so discuss dosing decisions with your physician or pharmacist.