Switching to Vortioxetine Improves Antidepressant Sexual Side Effects
Can Switching Antidepressants Resolve Sexual Side Effects?
A 3-month prospective real-life study published in the Journal of Clinical Medicine demonstrates that switching to vortioxetine significantly improves treatment-emergent sexual dysfunction (TESD) caused by SSRIs while maintaining antidepressant efficacy. The research shows that sexual dysfunction secondary to SSRIs occurs in over 60% of sexually active patients and over 80% of healthy volunteers, causing treatment discontinuation in more than 35% of patients, yet this critical side effect is rarely addressed in routine clinical practice.