Daily TMS Therapy: The Depression Treatment That Works in Just 6 Weeks
Does daily TMS work for treatment-resistant depression?
Yes. Daily left prefrontal TMS significantly improves depression symptoms in treatment-resistant patients, with response rates more than double those of sham treatment. This landmark randomized controlled trial demonstrated that patients receiving real TMS were 4 times more likely to achieve remission compared to those receiving fake treatment, establishing TMS as an effective therapy for depression that doesn’t respond to medications.
TMS works by delivering focused magnetic pulses to the left dorsolateral prefrontal cortex, a brain region that shows decreased activity in depression. The daily stimulation helps restore normal brain function and connectivity in areas responsible for mood regulation, executive function, and emotional processing.











