Supplementation

Supplementation

Articles tagged with "Supplementation".

Caffeine Myths Debunked: What Science Really Says (2024 Review)

Tags: Caffeine, Supplementation, Review, Ergogenic Aid

October 6, 2025

Dr. Kumar’s Take

This review organizes the most common misconceptions about caffeine supplementation and evaluates them against controlled research. It clarifies long-standing debates around tolerance, hydration, optimal timing, and whether delaying morning caffeine provides any measurable benefit. The data do not support delaying caffeine intake after waking.


Key Takeaways

  • Caffeine is ergogenic at lower doses than traditionally believed (as little as 2–3 mg/kg).
  • Hydration status is not impaired by moderate caffeine use.
  • Sleep disruption depends on timing and dose, not habitual use alone.
  • The idea of “waiting 90 minutes to caffeinate” lacks empirical support.
  • Habitual users continue to experience measurable performance benefits.

Actionable Tip

Focus on dose timing and total daily intake rather than arbitrary myths. Caffeine taken upon waking is physiologically appropriate and does not blunt alertness if sleep quality is adequate. Avoid caffeine within six hours of bedtime.

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The Effect of Vitamin D Supplementation on Depressive Symptoms in Adults: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Tags: Vitamin D, Cholecalciferol, Supplementation, Major Depressive Disorder, Depressive Symptoms, Systematic Review, Meta-Analysis, Randomized Controlled Trials

November 24, 2024

Introduction

This comprehensive systematic review and meta-analysis examined the efficacy of vitamin D supplementation in reducing depressive symptoms among adults. With depression affecting more than 320 million people worldwide and being the leading cause of disability globally, identifying effective adjunctive treatments is crucial for improving patient outcomes.

Background and Rationale

Vitamin D and Depression Connection

Vitamin D, traditionally known for its role in bone health, has emerged as a potential neurosteroid with significant implications for mental health. Following the discovery of vitamin D receptors in the brain, researchers have investigated its potential role in regulating neurophysiological processes associated with depression.

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