Psilocybin Meta-Analysis

Psilocybin Meta-Analysis

Articles tagged with "Psilocybin Meta-Analysis".

Psilocybin for Depression: BMJ Meta-Analysis Shows Significant Efficacy

Tags: Psilocybin Meta-Analysis, BMJ Depression Review, Psychedelic Medicine, Evidence-Based Treatment

November 23, 2025

Does psilocybin treat depression effectively?

Psilocybin shows significant efficacy for treating depression symptoms according to comprehensive BMJ meta-analysis.

Psilocybin works by activating serotonin receptors and promoting neuroplasticity, potentially resetting brain circuits involved in depression and providing rapid antidepressant effects.

What the data show:

  • Symptom reduction: substantial improvements in depression scores
  • Time to improvement: rapid effects compared to traditional antidepressants
  • Target population: effective when other treatments have failed
  • Evidence base: multiple clinical trials confirm effectiveness
  • Journal credibility: comprehensive BMJ meta-analysis provides definitive evidence

A comprehensive systematic review and meta-analysis published in The BMJ provides definitive evidence on psilocybin’s efficacy for treating depression symptoms, offering the most comprehensive assessment to date of this promising psychedelic treatment approach.

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