Can NSAIDs Help Kids with PANDAS Feel Better Faster?
Dr. Kumar’s Take:
This observational study found that children with PANDAS who took NSAIDs either before or early in a flare had shorter episodes of neuropsychiatric symptoms. These findings suggest a possible role for early anti-inflammatory treatment in managing this condition. While this was not a randomized trial, the results are compelling enough to justify further study.
Key Takeaways:
✔ NSAIDs taken early in a flare shortened symptom duration by about 2.6 weeks.
✔ Prophylactic NSAID use cut flare duration by around 4 weeks.
✔ Earlier treatment led to shorter flares, with each day of delay increasing the flare length slightly.
✔ No serious side effects were reported.