How Testosterone Therapy Improves Muscle Mass and Strength: Meta-Analysis Insights
Dr. Kumar’s Take
This meta-analysis makes it clear that testosterone therapy is not just about libido or energy. The consistent finding is that testosterone increases lean body mass and improves strength. That matters for men with hypogonadism, older adults with sarcopenia, and anyone concerned about frailty as they age. The dose, duration, and patient selection still matter, but the biological signal is strong: testosterone supports muscle health.
Key Takeaways
✔ Testosterone therapy consistently increased lean body mass in men.
✔ Strength gains were present but varied depending on the muscle group tested.
✔ The effect size was moderate, supporting clinical benefit in hypogonadal men.
✔ Longer treatment durations showed greater improvements.
