Metabolite Clearance

Metabolite Clearance

Articles tagged with "Metabolite Clearance".

Sleep Drives Brain Waste Clearance: Your Nightly Detox System

Tags: Sleep, Brain Health, Metabolite Clearance, Glymphatic System

October 22, 2025

Does Your Brain Have a Waste Disposal System That Works During Sleep?

Yes, and it’s one of the most important discoveries in sleep science. This landmark research revealed that sleep activates a sophisticated waste clearance system in the brain, dramatically increasing the removal of toxic metabolites that accumulate during waking hours. The brain’s “glymphatic system” increases its activity by 60% during sleep, flushing out cellular waste products including proteins associated with Alzheimer’s disease and other neurodegenerative conditions.

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