Maternal Mental Health

Maternal Mental Health

Articles tagged with "Maternal Mental Health".

Brexanolone Rapidly Improves Postpartum Depression, Anxiety, and Sleep

Tags: Brexanolone, Postpartum Depression, Maternal Mental Health, Rapid Treatment

November 23, 2025

A pooled analysis of three double-blind, randomized, placebo-controlled trials in the HUMMINGBIRD clinical program demonstrates that brexanolone infusion provides rapid and sustained improvement in depressive symptoms, anxiety, and insomnia in women with postpartum depression. Published in the Journal of Affective Disorders, this comprehensive analysis shows that brexanolone is associated with rapid improvement in depressive symptoms, with treatment effects sustained post-infusion, offering hope for mothers experiencing this debilitating condition.

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Real-World Brexanolone Outcomes: 12-Month Follow-Up Shows Sustained Benefits

Tags: Brexanolone Real-World, Postpartum Depression Outcomes, Maternal Mental Health, Long-Term Follow-Up

November 23, 2025

Does brexanolone work for postpartum depression in real practice?

Yes. Brexanolone produces approximately 85-90% improvement in depression symptoms, with 68.7% achieving treatment response and 46.7% achieving remission immediately after treatment. At 12-month follow-up, 73.4% maintained treatment response and 60.9% achieved remission. A real-world study of 150 women with postpartum depression (mean age 30 years) published in Women’s Health Reports found sustained benefits even in complex patients, with 91.3% taking concurrent psychiatric medications.

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