How Much Vitamin C Do We Need for Tissue Saturation? Blood vs. Leukocyte Levels Explained
Dr. Kumar’s Take:
While it’s well established that plasma vitamin C levels reach saturation with intakes of about 200 mg per day, this study and others show that higher intakes may be needed to fully saturate vitamin C in tissues—especially in white blood cells (leukocytes). This distinction is important, as plasma reflects short-term intake, while leukocyte vitamin C represents long-term tissue stores and may play a key role in immune function.