Sleep Deprivation Activates Inflammatory Genes and Cellular Stress Markers
How Does Sleep Deprivation Affect Gene Expression and Cellular Function?
Sleep deprivation significantly alters gene expression patterns, activating inflammatory genes and cellular stress pathways while suppressing genes involved in immune function and cellular repair. Research using genomic analysis reveals that even one night of sleep loss can change the expression of hundreds of genes, particularly those involved in inflammation, stress response, and circadian regulation. These molecular changes help explain how sleep deprivation increases disease risk and impairs cellular health at the most fundamental level.