Fundic Gland Polyps From PPIs: Should You Stop Treatment?
Should You Stop PPIs If You Develop Fundic Gland Polyps?
Most patients with PPI-associated fundic gland polyps can safely continue their proton pump inhibitor therapy if there is a clear medical indication, as these polyps are generally benign with very low malignant potential. However, patients with high-risk features (more than 20 polyps or polyps larger than 1 cm) may need closer monitoring or consideration of PPI discontinuation based on individual risk-benefit assessment.