How Slow Gastric Emptying Worsens GERD: Updated Research
How Does Slow Gastric Emptying Contribute to GERD Symptoms?
Delayed gastric emptying significantly worsens gastroesophageal reflux disease by increasing gastric volume and pressure, promoting reflux episodes, and creating a cycle where reflux further impairs gastric motility. This relationship explains why some GERD patients don’t respond well to acid suppression alone and may benefit from treatments that address gastric emptying dysfunction.
Dr. Kumar’s Take
This research highlights an often-overlooked aspect of GERD - the role of gastric emptying. When the stomach doesn’t empty properly, it creates a perfect storm for reflux: increased volume, higher pressure, and more opportunities for acid to flow backward. What’s particularly important is that this creates a vicious cycle - reflux can damage the vagus nerve and gastric motility, leading to even slower emptying. This explains why some patients need prokinetic agents or dietary modifications beyond just acid suppression.