Long-Chain Omega-3 PUFAs for Anxiety and Depression: Meta-Analysis
Do omega-3s help both anxiety and depression?
Yes. EPA-enriched omega-3 supplements significantly reduce depression symptoms when EPA makes up at least 60% of total EPA plus DHA, with optimal doses between 1 and 2 grams per day. A meta-analysis of 10 randomized controlled trials shows EPA is the key active component for antidepressant effects.
EPA works by reducing inflammation and supporting brain cell growth, which helps improve mood and reduce depressive symptoms.