Estrogen

Estrogen

Articles tagged with "Estrogen".

Hormones vs Antidepressants: Which Works Better for Menopausal Depression?

Tags: Menopausal Depression, Hormone Therapy, Estrogen, Antidepressants

November 15, 2025

Can Hormones Treat Depression Better Than Antidepressants?

For menopausal depression, the answer is often yes. Research shows that estrogen therapy can be more effective than traditional antidepressants for treating depression that develops during perimenopause and menopause. Estrogen works by directly addressing the hormonal root cause rather than just managing symptoms, often providing faster and more comprehensive relief.

Dr. Kumar’s Take

This research challenges the standard psychiatric approach of automatically prescribing antidepressants for menopausal women. When depression is hormonally driven, treating the underlying cause with estrogen makes more biological sense than trying to override hormonal effects with psychiatric medications. Many women have struggled for years on multiple antidepressants when what they really needed was hormone replacement. This represents a fundamental shift toward treating the cause rather than just the symptoms.

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The Mystery of Estrogen and Blood Vessel Health

Tags: Estrogen, Vascular Health, Endothelium, Cardiovascular Protection

November 15, 2025

Why Don’t We Fully Understand How Estrogen Protects Blood Vessels?

Despite decades of research showing that estrogen has protective effects on blood vessels, many fundamental questions remain unanswered. We know estrogen improves endothelial function, reduces inflammation, and promotes healthy blood flow, but the precise mechanisms and why timing matters so much for cardiovascular benefits are still being unraveled by researchers.

Dr. Kumar’s Take

This research highlights why hormone therapy decisions are so complex and why individualized care is essential. We have compelling evidence that estrogen protects blood vessels when given at the right time to the right women, but we’re still learning exactly how this works. This uncertainty has contributed to the confusion around hormone therapy’s cardiovascular effects, but it shouldn’t prevent women from accessing treatment when the evidence supports benefits.

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