Epidemiological Evidence

Epidemiological Evidence

Articles tagged with "Epidemiological Evidence".

Obesity-GERD Link: Review of 20 Years of Evidence

Tags: Obesity GERD, Epidemiological Evidence, Weight Reflux, BMI Gastroesophageal

November 7, 2025

What Does 20 Years of Research Tell Us About Obesity and GERD?

Two decades of epidemiological evidence consistently demonstrates a strong, dose-dependent association between obesity and gastroesophageal reflux disease across diverse populations worldwide. This comprehensive review of observational studies shows that the obesity-GERD relationship is robust, biologically plausible, and represents one of the most consistent findings in reflux disease research.

Dr. Kumar’s Take

This epidemiological review provides the foundation for understanding obesity as a primary GERD risk factor rather than just a contributing factor. The consistency across different populations, study designs, and geographic regions makes this one of the most reliable associations in gastroenterology. What’s particularly compelling is the dose-response relationship - the heavier someone is, the higher their GERD risk. This gives us confidence that weight management isn’t just helpful for GERD, it’s essential for many patients.

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