Omega-3 Fatty Acids Restore Balance on Gut-Brain Axis for Depression
How Do Omega-3 Fatty Acids Restore Balance Between Gut and Brain in Depression?
A comprehensive review published in Nutrients examines how omega-3 polyunsaturated fatty acids restore balance on the gut-brain axis and other interconnected biological pathways to improve depression. Major depressive disorder (MDD) is a complex, multifactorial condition involving dysregulation across immune, neural, and metabolic systems. Omega-3 polyunsaturated fatty acids (n-3 PUFAs), particularly eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), have emerged as promising therapeutic agents that work through multiple interconnected pathways to address the root causes of depression.