L-Theanine for Stress and Cognitive Function: Extended Clinical Trial Results
Do L-Theanine Benefits Persist with Long-Term Use? Extended Clinical Trial Evidence
L-theanine supplementation provides sustained improvements in stress-related symptoms and cognitive function with excellent long-term safety profile, this extended clinical trial confirms. Participants taking 200mg of L-theanine daily for 12 weeks maintained significant reductions in stress and anxiety levels (22% average reduction), with continued improvements in sleep quality, attention, and working memory throughout the extended study period. Importantly, no tolerance development was observed, and participants continued to experience benefits without needing dose increases. The extended trial also confirmed excellent safety with no significant adverse effects, making L-theanine suitable for long-term use in managing chronic stress and supporting cognitive performance.