Real-World Brexanolone Outcomes: 12-Month Follow-Up Shows Sustained Benefits
Does brexanolone work for postpartum depression in real practice?
Yes. Brexanolone produces approximately 85-90% improvement in depression symptoms, with 68.7% achieving treatment response and 46.7% achieving remission immediately after treatment. At 12-month follow-up, 73.4% maintained treatment response and 60.9% achieved remission. A real-world study of 150 women with postpartum depression (mean age 30 years) published in Women’s Health Reports found sustained benefits even in complex patients, with 91.3% taking concurrent psychiatric medications.