Alzheimer's Disease

Alzheimer's Disease

Articles tagged with "Alzheimer's Disease".

One Night Without Sleep Increases Alzheimer's Protein in the Brain

Tags: Sleep Deprivation, Amyloid Beta, Alzheimer's Disease, Brain Health

October 22, 2025

Does One Night of Sleep Loss Increase Alzheimer’s Proteins in Your Brain?

Yes, and the effect is immediate and measurable. This groundbreaking study used PET brain imaging to show that just one night of sleep deprivation significantly increases amyloid-beta accumulation in the human brain—the same toxic protein that forms plaques in Alzheimer’s disease. The research demonstrates that sleep isn’t just about feeling rested; it’s actively protecting your brain from the protein buildup that may lead to dementia decades later.

Read more

Sleep-Wake Cycle Controls Tau Protein Clearance in Brain and Spinal Fluid

Tags: Sleep Wake Cycle, Tau Protein, Brain Clearance, Alzheimer's Disease

October 22, 2025

Does Your Sleep-Wake Cycle Control Alzheimer’s Tau Protein Clearance?

Yes, and the regulation is remarkably precise. This groundbreaking research revealed that tau protein levels in brain tissue and cerebrospinal fluid fluctuate dramatically with the sleep-wake cycle, with concentrations nearly doubling during waking hours and decreasing during sleep. The study demonstrates that sleep actively clears tau proteins—the same proteins that form tangles in Alzheimer’s disease—providing another crucial mechanism by which sleep protects against neurodegeneration.

Read more