Oxygen Therapy During ADL Rehabilitation in Severe COVID-19

Oxygen Therapy During ADL Rehabilitation in Severe COVID-19

Patient receiving oxygen therapy during rehabilitation exercises

How Long Do Severe COVID Patients Need Oxygen During Daily Activities?

About 7 weeks on average. This prospective study of 23 severe-to-critical COVID-19 patients found supplemental oxygen was needed for 48.6 days during activities of daily living. Showering required oxygen the longest (47.7 days), while dressing weaned first (38.4 days). Mechanical ventilation history and exertional desaturation predicted prolonged oxygen needs.

Recovering from severe COVID-19 involves regaining the ability to perform basic self-care tasks. This Singapore-based study tracked exactly how long patients needed supplemental oxygen during specific activities, providing valuable data for discharge planning and patient expectations.

What the Data Show

Patient Characteristics:

  • 23 patients enrolled with severe-to-critical COVID-19
  • Age: Mean 69.5 years (range 46-85), 60.9% over age 65
  • Sex: 69.6% male (16 men, 7 women)
  • Premorbid status: 100% independent in basic ADLs
  • Vaccination: 52.2% unvaccinated, 17.4% partial, 30.4% fully vaccinated
  • Respiratory support: 30.4% required mechanical ventilation, 69.5% non-invasive ventilation

Oxygen Weaning Duration by Activity:

ActivityMean DaysSDRank
Dressing38.417.1Shortest
Ambulation (10m)Intermediate-2nd
ToiletingIntermediate-3rd
Showering47.718.1Longest
Total average48.618.3-

Longest individual case: 93 days for showering

Key observation: After rehabilitation transfer, all patients only needed oxygen during task performance, not at rest.

Complications During Rehabilitation:

  • Exertional dyspnea: 100% (all patients)
  • Exertional desaturation: 87.0%
  • Platypnea Orthodeoxia Syndrome (POS): 82.6%
  • Postural hypotension: present in subset
  • Limb weakness: present in subset

Functional Outcomes at Discharge:

MeasureResult
FIM score gain28.2 ± 17.3 points
Independence in all basic ADLs65.2%
FAC 4-5 (independent ambulation)82.6%
FAC 3 (supervision required)13.0%
Discharge home100%
Median rehabilitation stay20 days
Median total hospital stay52 days

Follow-Up at 2-6 Months (n=21):

OutcomeResult
Resting SpO298.1% ± 1.3% (normalized)
POS resolved100%
Exertional dyspnea persisting28.5%
Exertional desaturation persisting19.0%
Independent ambulation95.2%
Unlimited community mobility61.9%
Limited community mobility33.3%
Homebound4.8%
30-second Chair Stand Test11.6 ± 3.3 (below age norms)
Return to work (of 7 employed)42.9% (3/7)

Dr. Kumar’s Take

This study provides practical benchmarks for rehabilitation teams. The nearly 10-day gap between dressing (38.4 days) and showering (47.7 days) makes clinical sense. Showering combines standing, humid air, upper body movement, and physical exertion. Dressing was assessed seated, reducing oxygen demands.

The finding that showering is rate-limiting for discharge has real implications. If a patient can handle dressing and toileting but still desaturates during showering, they may not be ready for independent living. This helps frame realistic expectations for patients and families.

I find the correlation data particularly useful. Mechanical ventilation history (standardized coefficient 0.77-0.83) strongly predicts prolonged oxygen needs. This lets us counsel patients early: “You were on a ventilator, so expect a longer path to oxygen independence.”

The 2-6 month follow-up shows most respiratory symptoms resolve, but physical deconditioning persists. Most patients had below-normal 30-second chair stand scores, and only 43% returned to work. This suggests rehabilitation efforts should extend beyond oxygen weaning.

Why Different Activities Have Different Recovery Times

Dressing (shortest at 38.4 days):

  • Performed seated
  • Limited lower limb involvement
  • No environmental factors affecting oxygen

Showering (longest at 47.7 days):

  • Standing position requires more oxygen
  • Humid, warm environment reduces partial oxygen pressure
  • Upper and lower limb movement combined
  • Enclosed space builds moisture
  • Represents highest physiological demand

Ambulation and Toileting (intermediate):

  • Mix of standing and sitting
  • Varying levels of exertion

Predictors of Prolonged Oxygen Need

Multivariable Analysis Results:

FactorAssociationSignificance
Mechanical ventilationStandardized B: 0.77-0.83P<0.001 for all ADLs
Exertional desaturationStandardized B: 0.44-0.60P=0.001-0.037
ICU admissionSignificant on correlationNot significant in multivariable
Age, sex, comorbiditiesNot significant-
Vaccination statusVariableMixed findings

Interpretation: Prior mechanical ventilation was the strongest predictor of prolonged oxygen therapy across all activities. This likely reflects more severe initial lung injury and persistent pulmonary lesions including fibrosis.

Practical Strategies for Faster Weaning

The researchers suggest several approaches based on their findings:

Respiratory maneuvers: Techniques to improve ventilation and gas exchange during activities.

Energy conservation:

  • Activity pacing
  • Performing tasks seated when possible
  • Breaking tasks into stages

Environmental modifications for showering:

  • Ventilator fan in bathroom
  • Opening door/window to reduce humidity
  • Shower chair to reduce standing demands
  • Cooler water temperatures

Staged progression: Start with less demanding activities (dressing) before tackling showering.

Long-Term Implications

Respiratory:

  • Resting oxygen normalized in all patients by 2-6 months
  • About 19% still had exertional desaturation
  • SpO2 nadirs remained above 92% and recovered with rest

Functional:

  • Most achieved independent ambulation (95.2%)
  • But one-third had limited community mobility
  • Physical deconditioning persisted (below-norm 30CST scores)
  • Only 43% of previously employed patients returned to work

Implication: Recovery to premorbid condition at 2-6 months was not achieved in most subjects, despite respiratory improvement. Continued rehabilitation support may be needed.

Study Limitations

  • Small sample size (23 patients)
  • Single rehabilitation center in Singapore
  • ADLs not assessed daily (some assessed 2-3 days apart)
  • 6-minute walk test not used at follow-up (may have under-detected exertional issues)
  • 2 patients lost to follow-up

Practical Takeaways

  • Expect about 7 weeks of oxygen support during daily activities after severe COVID
  • Showering ability is likely the rate-limiting factor for home discharge
  • Mechanical ventilation history indicates longer oxygen needs
  • Exertional desaturation during rehab predicts prolonged support
  • All basic ADL oxygen needs typically resolve before discharge
  • Respiratory symptoms largely resolve by 2-6 months
  • Physical deconditioning may persist longer than respiratory issues
  • Consider environmental modifications for showering
  • Monitor oxygen during activities, not just at rest

FAQs

Why does showering require oxygen support the longest?

Showering combines multiple challenges: standing position (higher oxygen demand than sitting), warm humid environment (reduced partial oxygen pressure), upper and lower limb movement, and enclosed space with moisture buildup. This creates the highest total oxygen demand among daily activities. The study found showering took nearly 10 days longer than dressing to wean from oxygen support.

Can patients speed up oxygen weaning?

The study was observational, not interventional, so it can’t directly answer this. However, the rehabilitation program (10-15 hours/week of physical and respiratory conditioning) helped patients achieve independence. Environmental modifications (bathroom ventilation, shower chairs), energy conservation techniques, and respiratory maneuvers may help. Individual timelines vary based on illness severity.

What does it mean if oxygen drops during activities but not at rest?

This is common in COVID-19 recovery. The lungs may adequately oxygenate blood at rest but cannot meet increased demands during exertion. This phenomenon - exertional desaturation without resting hypoxemia - affected 87% of patients in this study. Supplemental oxygen during activities bridges this gap until lung function improves.

How can I tell if I’m ready to shower without oxygen?

Healthcare providers typically monitor oxygen saturation during activity. The study used SpO2 consistently above 92% as the threshold for oxygen independence. Home pulse oximeters can help monitor, but discuss specific parameters with your medical team. Consider environmental modifications (ventilation, shower chair) even after oxygen weaning.

Bottom Line

This prospective study of 23 severe-to-critical COVID-19 patients found supplemental oxygen was needed for an average of 48.6 days during activities of daily living. Showering required oxygen support the longest (47.7 days) while dressing weaned first (38.4 days), making showering the rate-limiting activity for safe discharge. Mechanical ventilation history and exertional desaturation strongly predicted prolonged oxygen needs. While respiratory symptoms largely resolved by 2-6 months follow-up, physical deconditioning persisted, with most patients showing below-normal strength and only 43% returning to work. This data helps clinicians set realistic recovery timelines and plan appropriate discharge criteria.

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