Mediterranean Diet with Olive Oil or Nuts Reduces Heart Disease Risk: A Landmark Study

Mediterranean Diet with Olive Oil or Nuts Reduces Heart Disease Risk: A Landmark Study

Mediterranean diet study on heart disease prevention

Dr. Kumar’s Take:

A major clinical trial confirms what nutrition experts have long suspected: eating a Mediterranean diet rich in olive oil or nuts can lower the risk of heart disease. This study, which followed over 7,400 people at high cardiovascular risk, found that those who ate a Mediterranean diet had up to a 31% lower risk of heart attack, stroke, or cardiovascular death.

Actionable Tip: If you’re looking to protect your heart, start by switching to a Mediterranean diet with plenty of extra-virgin olive oil or a daily handful of nuts. These small changes can reduce your absolute risk of heart disease by up to 2.1 percentage points over five years.

Brief Summary:

The PREDIMED study was a large, multi-center trial conducted in Spain that tested the impact of a Mediterranean diet supplemented with either extra-virgin olive oil or nuts compared to a low-fat diet on heart disease prevention.

Over 4.8 years, researchers found that participants who followed the Mediterranean diet had a significantly lower risk of cardiovascular events than those who were advised to eat a low-fat diet.

Key Takeaways:

Mediterranean diet with extra-virgin olive oil reduced cardiovascular risk by 31% (Absolute Risk Reduction: 2.1%).
Mediterranean diet with nuts reduced risk by 28% (Absolute Risk Reduction: 1.7%).
Both diets outperformed a traditional low-fat diet for heart disease prevention.
No calorie restriction was required—participants simply followed the diet’s principles.

Study Design:

  • Participants: 7,447 men (55–80 years old) and women (60–80 years old) at high cardiovascular risk.
  • Intervention Groups:
    1. Mediterranean diet + extra-virgin olive oil (EVOO) (1 liter per week)
    2. Mediterranean diet + mixed nuts (30g/day: walnuts, hazelnuts, almonds)
    3. Control diet (low-fat diet recommendations)
  • Follow-up Period: 4.8 years
  • Primary Outcome: Major cardiovascular event (heart attack, stroke, or cardiovascular death).

Results:

Heart attacks, strokes, and cardiovascular deaths were significantly lower in both Mediterranean diet groups compared to the low-fat diet group.
The Mediterranean diet with olive oil group had a 31% lower risk (HR: 0.69).
The Mediterranean diet with nuts group had a 28% lower risk (HR: 0.72).
Absolute Risk Reductions (ARR):

  • Mediterranean diet with extra-virgin olive oil: 2.1% (5.7% → 3.6%)
  • Mediterranean diet with nuts: 1.7% (5.7% → 4.0%)

Participants maintained these benefits without restricting calories.

How the Mediterranean Diet Protects Your Heart:

The Mediterranean diet is known for its anti-inflammatory and heart-protective effects. Key factors include:

  • Healthy fats from olive oil and nuts help lower LDL and increase HDL.
  • Rich in antioxidants that reduce oxidative stress and inflammation in the arteries.
  • High fiber intake from vegetables, legumes, and whole grains supports heart health.
  • Moderate fish and poultry intake provides lean protein.

Mediterranean Diet and Heart Disease – Explores the role of the Mediterranean diet in reducing cardiovascular risk and improving heart health.

Mediterranean vs. Low-Fat Diets for Heart Health – Compares the cardiovascular benefits of the Mediterranean diet versus a low-fat diet in heart disease prevention.

Frequently Asked Questions:

Who benefits most from the Mediterranean diet?

The study focused on people at high risk of heart disease (e.g., those with diabetes, high blood pressure, or obesity). However, research suggests that anyone can benefit from adopting this eating pattern.

Do I need to count calories on this diet?

No! Unlike many diets, the Mediterranean diet in this study did not require calorie restriction. The emphasis was on quality of food rather than quantity.

What’s the best way to start a Mediterranean diet?

Swap vegetable oils for extra-virgin olive oil in cooking.
Eat a handful of nuts daily (walnuts, almonds, hazelnuts).
Increase vegetables, fruits, and whole grains in your meals.
Reduce processed foods and sugar.

Can the Mediterranean diet help with weight loss?

While this study focused on heart disease prevention, other research has shown that people often lose weight naturally when following a Mediterranean diet due to its high fiber and healthy fat content.

Conclusion:

The Mediterranean diet is one of the best diets for heart health. This study provides strong clinical evidence that eating more olive oil and nuts can significantly reduce your risk of heart disease.

The absolute risk reduction (ARR) of up to 2.1% over five years means that for every 100 people following this diet, about 2 fewer will experience a major heart event compared to those on a low-fat diet.

If you’re looking for a long-term, sustainable way to improve your health, this is the diet to follow.

Read the full study here