Dr. Kumar’s Take
This trial shows that a standardized Tongkat Ali extract called Physta can lift testosterone and improve measures of vitality in older men. Effects were most meaningful in men with lower starting levels. It is not a substitute for medical therapy in true hypogonadism, but it can be a useful tool alongside sleep, training, and nutrition.
Key Takeaways
✔ Physta increased total testosterone compared with placebo in aging men.
✔ Participants reported better vitality and sexual well being scores.
✔ Safety profile was favorable with few mild adverse events.
✔ Benefits were stronger in men with lower baseline testosterone.
Actionable Tip
For older men with low energy and borderline hormone levels, consider discussing standardized Tongkat Ali (Physta) with your clinician. Use evidence based doses, check product quality, and track labs and symptoms over 8 to 12 weeks.
Study Summary
A multicenter, randomized, double blind, placebo controlled trial evaluated Eurycoma longifolia (Physta) in aging men. Participants received a daily standardized dose for several weeks. Primary outcomes were serum testosterone and validated vitality or sexual health questionnaires. Compared with placebo, Physta raised testosterone and improved patient reported outcomes.
Study Design and Methods
- Population: Community dwelling men in midlife and older age.
- Intervention: Standardized Tongkat Ali extract Physta taken once daily.
- Control: Matching placebo.
- Duration: Several weeks of treatment with baseline and endline assessments.
- Outcomes: Total testosterone, sometimes free testosterone, and questionnaires of vitality, mood, and sexual function.
- Safety: Routine adverse event monitoring and standard laboratory tests.
Results
- Hormones: The Physta group showed a statistically significant rise in total testosterone versus placebo. Free testosterone trends favored Physta when measured.
- Patient reported outcomes: Vitality and sexual well being scores improved more in the Physta group.
- Tolerability: Few mild events such as transient stomach discomfort. No serious safety signals were reported in this time frame.
How Tongkat Ali Physta May Raise Testosterone
Tongkat Ali appears to influence several pathways that support androgen status:
- Lower cortisol and stress load: By reducing cortisol, the body shifts the testosterone to cortisol balance toward anabolism.
- Leydig cell support: Compounds in the extract may stimulate enzymes of testicular steroidogenesis, leading to more testosterone output.
- Possible SHBG effects: Some data suggest modest reductions in sex hormone binding globulin, which can increase bioavailable testosterone.
- Adaptogenic and antioxidant effects: Improved cellular stress handling may protect hormone producing cells and support energy.
Practical Considerations
- Who might benefit: Older men with fatigue, low vitality, and borderline low testosterone who want a trial of a standardized herbal option.
- Dosing: Use the standardized Physta dose studied on label. Avoid non standardized powders.
- Monitoring: Recheck testosterone, hematocrit, lipids, and symptoms after 8 to 12 weeks. Continue only if there is clear benefit and good tolerance.
- Stacking with lifestyle: Pair with resistance training, protein intake, and sleep hygiene to amplify results.
Related Studies and Research
Podcast: Testosterone Replacement Therapy Explained – How to think about hormones, goals, and monitoring.
Tongkat Ali Raises Testosterone: Meta-Analysis – Big-picture evidence across multiple clinical trials.
Ashwagandha and Hormones in Aging Men – Crossover trial in older, overweight men.
Ashwagandha Boosts Strength and Recovery – Strength, muscle size, and recovery improvements with training.
Frequently Asked Questions
How fast can I expect changes?
Trials reported benefits within 4 to 8 weeks. Some men notice energy and drive earlier, objective lab changes follow on schedule.
Is Tongkat Ali as strong as testosterone therapy?
No. Effects are modest compared with TRT. It is best for men with borderline levels or stress related reductions.
Can I take it with other supplements?
Often yes, but avoid overlapping stimulants. Discuss with your clinician, especially if you take anticoagulants or have liver or kidney disease.
Are the effects permanent?
Benefits depend on continued use and on lifestyle inputs like sleep and training. Stopping the supplement usually returns levels toward baseline.
Conclusion
In aging men, standardized Tongkat Ali Physta raised testosterone and improved vitality measures compared with placebo. It offers a well tolerated, evidence based option for men who want a natural approach, especially when paired with strength training, nutrition, and good sleep.